QAbyMail Service for Patient Safety in Radiation Therapy

mgsresearch.com

d.b.a. 3D Dosimetry

QAbyMail™ Service: High-Definition 3D End-to-End QA for Patient Safety in Radiation Therapy and Radiosurgery

Email: support@mgsresearch.com

CrystalBalls™:

Polymer gel dosimeters:
Sealed inside glass spheres
Standard human head size
Radiochromic
Self-developing
Muscle-equivalent

Time-efficient workflow:
Instant setup
Standard size
No cables
No electronics
Easy packaging

Readout:
Laser CT scanning
at 3D Dosimetry Lab

The CrystalBall™ mounted in a QA stand and ready for simulator CT

The CrystalBall™ set up for Proton Therapy QA

CrystalBall™ mounted in an SRS head frame


Applications:
Commissioning
Annual E2E
Machine QA
Patient QA

Modalities:
SRS
SBRT
CyberKnife
GammaKnife
IMRT
VMAT
RapidArc
Halcyon
MR-Linac
Proton Therapy
Heavy Ion Therapy

Unique for:
Multiple brain metastases

Specifications:

1. Resolution:
(0.5mm)^3 voxel

2. Dosimetric accuracy
(at 95% confidence):
0.5% relative
2% absolute

3. Sphere diameter (OD):
166 mm standard
230 mm max

4. Wall thickness: 2-3 mm

5. Active diameter:
Sphere's OD less 20 mm

QAbyMail ™ Service Description:

1. Customers return exposed CrystalBalls and DICOM files to 3D Dosimetry Lab for laser CT scanning and QA analysis.

2. High-definition 3D QA reports are returned by email.

3. Reports may be customized but normally include:

a. Volume histograms & passing rates of 3D gamma;

b. Volume histograms and voxel statistics for:

i. Dose Difference

ii. Distance-to-Agreement

c. Detected shifts of dose cloud's center of mass

d. Overlays of planned vs measured:

i. 3D and 2D isodoses

ii. Profiles

iii. Dose-Volume histograms

e. Interactive 3D maps of:

i. Dose Difference

ii. Distance-to-Agreement

iii. 3D gamma


EXAMPLE  RESULTS

Overlay of 3D isodose surfaces (here shown at 70% isodose level)

Coronal frontal view of overlaid 3D isodose surfaces (VMAT of six brain metastases, PTV#4)

Overlay of 2D (sagittal left) isodose lines (VMAT of six brain metastases, PTV#4)

Overlay of I-S profiles (VMAT of six brain metastases, PTV#4)

3D gamma histogram for PTV#4 (VMAT of six brain metastases)

3D DTA histogram for PTV#4 (VMAT of six brain metastases)

3D Dose Difference histogram for PTV#4 (VMAT of six brain metastases)

CrystalBall™ 3D QA report summary for one PTV in a six brain-metastases VMAT

Proton PBS IMPT. (a) 3D isodose surfaces at 50% dose level. Red - plan, blue - measurement; (b) Coronal isodoses. Solid - plan, dotted - measurement. (c) I-S profile overlay. Red - plan, blue - measurement, yellow - dose difference, magenta - DTA, cyan - 3D gamma.

The CrystalBall™ End-to-End QA detects and measures any and all clinically significant cumulative errors that may originate anywhere during radiation therapy or radiosurgery treatment planning and delivery process; errors that may be located anywhere within the treated volume.

QAbyMail™ Service: High-Definition 3D End-to-End QA for Patient Safety in Radiation Therapy and Radiosurgery​​

The CrystalBall™ End-to-End QA detects and measures any and all clinically significant cumulative errors that may originate anywhere during radiation therapy or radiosurgery treatment planning and delivery process; errors that may be located anywhere within the treated volume.

QAbyMail™ Service: High-Definition 3D End-to-End QA for Patient Safety in Radiation Therapy and Radiosurgery